First Flight Biosciences offers assays and assay development/validation services to our clients throughout the world. These services cover all major target classes including GPCRs & other receptors, kinases, Epigenetics & other enzymes, ion channels and transporters, etc., in a high-throughput screening (HTS) format. Our experienced teams define and optimize an assay into robust and reproducible outcomes for a successful implementation of development phase prior to validation phases. At First Flight Biosciences, validation process will generate a validated protocol which will include experiments for confirming assay parameters and testing that the devices used for the assay that would meet the performance criteria for the intended usage. At the end, an assay development protocol and validation report will be generated for the clients.

First Flight Biosciences specializes in both biochemical assays and cell-based functional assays, which play a pivotal role in the decision to move tested compounds from in vitro to in vivo pharmacology for a variety of drug targets. Our assay technologies include but not limited to:

1 FLIPR based calcium assays for GPCRs;

2 Reporter gene assays;

3 cAMP based assays for GPCRs;

4 Beta Arrestin based assays for GPCRs;

5 Membrane receptor binding assays;

6 GTPγS binding assay;

7 Electrophysiology assays (patch clamp);

8 Membrane potential dye-based assays for ion channels;

9 Biochemical assays for kinase and other enzymes;

10 Cell-based kinase assays;

11 Radiometric assays for various targets;

12 High content assays;

13 Cellular phenotypic assays;

14 Cytotoxicity assays (HTS).